The World Colostrum Company -------------------Rebornne First Colostrum
NEW ZEALAND MILK HOME ---Rebornne New Zealand Limited
   

New Zealand is renowned as a clean, green country. With clean air, pasture and water, it's the ideal environment for Rebornne First Colostrum.

Dairy farms in New Zealand are typically owned and farmed by families with perhaps some assistance from young farmers in a share-milking position.

Dairy herds are predominantly Jerseys and Holstein-Fresians which graze on healthy grass pastures, even in winter.

This all-year outdoor pasture farming results in dairy products that are acclaimed worldwide for their goodness, nutrition, energy and taste.

 

Products

Quality Story

Colostrum Information

Research

Strength & Fitness

Products Efficacy

FAQ'S

Colostrum News

Secure Online Ordering

Best Colostrum

ACTIVE FIRST FOOD

Liquid Colostrum

Home

Health Links


Rebornne First Colostrum

The world Colostrum Company

 

American

France

Germeny

China

England

Japan

Australia

Canada

Singapore

New Zealand

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

 

 

 

 

 

 

 

 

 

 

Health products to make your family happy every day

 

New Zealand - the best environment in the world for dairy products
New Zealand Dairy Farms For All Over World Health! --New Choice From New Zealand ! New Life From Rebornne!

Rebornne First Colostrum is made with colostrum supplied by NZDB, NZDB have the most modern and largest dairy products manufacturing sites in the world. It has the world's largest spray dryers, including two that can each process in excess of 20 tonnes of milkpowder per hour. Which originates from New Zealand healthy, pollution-free, and pasture-fed cows in the first 72 hours after birth.


Unlike other major dairy nations, New Zealand's dairy industry is entirely pasture based. The warm, moist climate promotes pasture growth, and relatively mild winter temperatures enable the country's 3.2 million cows to be grazed outdoors all year around. With no need of supplementary feeding, so safe from BSE and mouth and foot diseases
This product contains an abundance of immune substances, especially immunoglobulins, as well as growth factors, protein, calcium, essential fatty acid, vitamins, microelements, and other nutrients essential for human beings.


It does not contain chemical preservatives, and is a natural pollutant-free health food product. It is convenient to consume and suitable for children, pregnant/after-birth women, elderly, and all busy people. It is also a good supplement for people recovering from illness and sports-people on training programs.


The world's leading chilled temperature collection and storage system, and low heat spray dried technology are employed to ensure the biological activity of Rebornne TM Colostrum milk powder. This product is produced under strict Good Manufacturing Practice (GMP) which guarantees the product quality and ensures only the best is made available.

  • You Should Know ONE

Colostrum
Rebornne First Colostrum is from New Zealand cows, which is far superior to any other colostrum because New Zealand has the purest climate, and its pasture-fed cows are free of pesticides, antibiotics, and diseases like BSE and foot-and-mouth. The processing methods used protect the nutritional integrity of the product.
Clinicallyextracted under the most exacting of standards,
Rebornne First Colostrum contains all the vital constituents that make that initial foodstuff the primary nutritional source for the body immune system.
Rebornne First Colostrum can be taken by young and old alike as well as athletes and sports people. With the abundance of nutrients contained in it, Colostrum is an effective aid to any nutritional regime or daily supplementation and provides a foundation for physical health based on the ultimate blueprint: Nature.


Rebornne First Colostrum :
1,contains all necessary immune factors plus growth factors
2,contains a variety of vitamins and minerals
3,fights and removes bacterial invaders in the intestinal tract
4,contains the Insulin-like growth factor IGF-1
5,is associated with athletic endurance
6,is suitable for people recovering from illness, especially when combined with Fatty Acid Complex
7,is suitable for athletes

  • You Should Know TWO

Natural dietary supplements are believed by many to relieve ailments and promote good health and a feeling of well being. However, the products described on this website are not offered to diagnose, treat, cure or prevent disease.Rebornne First Colostrum Products provides the information contained herein for all to review, so those interested may further educate themselves about natural, non-toxic supplements that may enhance their quality of life. Any decisions on how to use this information is left to the sole discretion of the reader and/or the readers personal physician.

Rebornne First Colostrum Products assume no responsibility in the correct or incorrect use of this information. All liabilities related to use of this information for self-prescribing or diagnosing without proper advice of a qualified physician or other qualified health care practitioner is hereby expressly disclaimed. We recommend seeking the advice and assistance of a health care professional before making any major changes to your health care programme.

 

 

Rebornne First Colostrum

Your First Food!

Colostrum Research(Bovine Colostrum):

What is in Colostrum?
Immune Factors:
Medical and clinical studies show immune factors in colostrum fight viruses, bacteria, yeast, fungus, allergens and other toxins.

Immunoglobulins:
Immunoglobulins have been shown to provide a superior defense in both treatment and prevention of viral infections, bacterial infections, allergies, fungus and yeast. There are five types of immunoglobulins present in colostrum, specifically IgA, IgD, IgE, IgG, & IgM. Bovine colostrum contains mostly IgG with very small amounts of IgA, IgD, IgE, and IgM. Human colostrum typically contains 2% IgG content, while bovine colostrum can have from 8% to above 25% IgG content. These are protein molecules that are effective in fighting bacterial and viral infections (colds, flu, etc.), parasites, and yeast. Immunoglobulins are energizing elements in colostrum that are anti-inflammatory in nature. High quality bovine colostrum contains a minimum of 20% immunoglobulins.

Antibodies:
Colostrum has been shown to contain specific antibodies to more than 19 specific disease-causing pathogens including; rotavirus, h. pylori, cryptosporidium, salmonella, candida, streptococcus, staphylococcus and E. coli.

PRP (Proline-rich Polypeptide):
Shown to help regulate the thymus gland (bodiescentral command for the immune system). PRP can stimulate a weakened immune system, as well as balance an overactive immune system, as in the case of many autoimmune diseases.

Lactoferrin:
An iron-binding protein with antiviral, antibacterial, anti-inflammatory properties. Lactoferrin has been implicated in the treatment of such diseases as cancer, HIV, herpes, chronic fatigue, candida albicans and other infections.

Glycoproteins: (protease and trypsin inhibitors)
Protect the immune and growth factors in colostrum from destruction by the digestive juices in the stomach and intestinal tract.

Lactalbumins:
Research indicates tremendous possibilities that Lactalbumins can be highly effective against numerous forms of cancer and viruses. Lactalbumin has also been shown in vulnerable subjects to raise brain serotonin activity, reduce cortisol concentration, and improve mood under stress.

Cytokines:
Interleukin 1 & 6, Interferon Y & Lymphokines:
Chemicals that are involved in cell-to-cell communication, antiviral and anti-tumor activity and regulation and intensity of immune responses. Cytokines help increase T-cell activity and stimulate production of immunoglobulins. One cytokine, interleukin-10, is a potent anti-inflammatory agent that has been shown to have a profound effect on pain relief. Interleukins have shown particular promise in fighting cancer.

Lysozymes:
Helps protect the body from bacterial infections. Lysozyme has actually been shown to destroy bacteria on contact. May be an effective topical antibiotic.

Growth Factors:
Medical studies have shown that the vital growth factors from bovine colostrum are practically identical to human colostrum in composition. Furthermore, it has been shown that growth factors stimulate normal growth, as well as help regenerate and accelerate the repair of aged or injured muscle, skin collagen, bone, cartilage and nerve tissues. Growth factors also stimulate the body to burn fat for fuel instead of the body's own muscle tissue in times of fasting (diet) and build lean muscle. In addition, growth factors can be used as an effective topical application for burns, injuries and skin rejuvenation.

Epithelial Growth Factor (EGF):
EGF is instrumental in protecting and maintaining the skin. Along with the other growth factors in colostrum, EGF can stimulate normal skin growth and repair cellular tissue.

Insulin-like Growth Factor I and II: (IGF-I & IGF-II)
IGF I & II are the most abundant growth factors in colostrum. They affect how the body uses fat, protein and sugar. IGF-I is one of the only substances known to stimulate the repair and growth of DNA and RNA, making it one of the most powerful anti-aging substances. IGF-I has been clinically proven to help increase lean muscle mass and may help regulate blood sugar and cholesterol levels.

Transforming Growth Factors A & B: (TGF A & B)
TGF stimulates the proliferation of cells in connective tissue and assists in the formation of bone and cartilage. It is also showing promise as a therapeutic agent in bone and wound healing. TGF can help repair tissue and may support the development of growth of the lining of the gut.

Platelet-Derived Growth Factor: (PDGF)
PDGF has been shown to help with cell division in connective tissue, smooth muscle, and fibroblasts. It may also assist in neuron survival and regeneration.

Vitamins & Minerals
The vitamins and minerals in colostrum are naturally occurring and naturally balanced.

Athletic Performance

Buckley JD, et al. Effect of An Oral Bovine Colostrum Supplement Intact on Running Performance.

Burke E. (1996) Colostrum as an athletic enhancer and help for AIDS. Nutrition Science News.

Mero A, et al. (1997) Effects of bovine colostrum supplementation on serum IGF-1, IgG, hormone, and saliva IgA during training. Journal of Applied Physiology. 83: 1144-1151.
PubMed Reference
UI: 97479511

Sparling PB, Nieman DC, O'Connor PJ. (1993) Selected scientific aspects of marathon racing : an update on fluid replacement, immune function, psychological factors and the gender difference. Sports Medicine. 15: 116-132.
PubMed Reference
UI: 93189945

Berk LS, Nieman DC, Youngberg WS, et al. (1989) The effect of long endurance running on natural killer cells in marathoners. Medicine and Science in Sports and Exercise. 22: 207-212.
PubMed Reference
UI: 90286868

Antonio, J., Sanders, M. and Van Gammeren, D. The Effects of Bovine Colostrum Supplementation on Body Composition and Exercise Performance in Active Men and Women. Nutrition 17:243-247, 2001.
PubMed Reference

General Information

Bitzan MM, Gold BD, Philpott DJ, et al. (1998) Inhibition of Helicobacter pylori and Helicobactor mustelae binding to lipid receptors by bovine colostrum. The Journal of Infectious Diseases. 177: 955-961.
PubMed Reference
UI: 98194591

Cavalli-Sforza LT, Strata A. (1987) Double-blind study on the tolerance of four types of milk in lactose malabsorbers. Human Nutrition: Clinical Nutrition 40C: 19-30.
PubMed Reference
UI: 87194017

Joseph M. and Flesch A. (1998) Research shows colostrum to be one of nature's most potent, broad-spectrum substances. Chiropractic Journal.

 

Cenacchi T, Baggio C, and Palin E. (1987) Human tolerability of oral phosphatidylserine assessed through laboratory examinations. Clinical Trials Journal. 24.

Ghidini A, Hicks C, Lapinski RH, Lockwood CJ. (1997) Morbidity in the preterm infant with mature lung indicies. American Journal of Perinatology. 14: 75-78.
PubMed Reference
UI: 97406454

Jochims K, Kaup FJ, Drommer W. (1994) Immunoelectron microscopical demonstration of the absorption of colostral IgG by small intestinal enterocytes in newborn rats. Research in Veterinary Science. 57: 146-151.
PubMed Reference
UI: 95116714

Efigenia M, Povoa B, Moraes-Santos T. (1997) Effect of heat treatment on the nutritional quality of milk proteins. International Dairy Journal. 7:609-612.

 

Klagsbrun, M. (1978) Human milk stimulates DNA synthesis and cellular proliferation in cultured fibroblasts. Proceedings of the National Academy of Sciences, USA. 75: 5057-5061.
PubMed Reference
UI: 79116260

Kume S, Tanabe S. (1993) Effect of parity on colostral mineral concentrations of holstein cows and value of colostrum as a mineral source for newborn calves. Journal of Dairy Science. 76:1654-1660.
PubMed Reference
UI: 93315710

Le Dividich J, Herpin P, Paul E, Strullu F. (1997) Effect of fat content of colostrum on voluntary colostrum intake and fat utilization in newborn pigs. Journal of Animal Science. 75:707-713.
PubMed Reference
UI: 97233497

Li-Chan E, Kummer A, Losso J, Kitts D, Nakai S. (1995) Stability of bovine immunoglobulins to thermal treatment and processing. Food Research International. 28: 9-16.

Nitsch A, and Nitsch F. (1998) The clinical use of bovine colostrum. Journal of Orthomolecular Medicine. 13.

Wit JN. (1998) Nutritional and functional characteristics of whey proteins in food products. Journal of Dairy Science. 81:597-608.
PubMed Reference
UI: 98226987

Walker WA. (1999) What is the role of nucleotides and polyamines in breast milk? Acta Paediatrica. 88:1313-1315.
PubMed Reference
UI: 20089938

McConnell MA, Brooks HJL, Borissenko MB, Buchan GA. A comparative study of immunoglobulin levels and anti-inflammatory activity in four milk products. Journal of Dairy Science, Publication forthcoming.

 

Warny M, Fatima A, Bostwick E, et al. (1998) Bovine immunoglobulin concentrate-Clostridium difficile retains C difficile toxin neutralising activity after passage through the human stomach and small intestine. Gut. 44(2):212-7.
PubMed Reference
UI: 99112987

Wieczorek Z, Zimecki M, Janusz M, Staroscik K, Lisowski J. (1979) Proline-rich polypeptide from ovine colostrum: its effect on skin permeability and on the immune system. Immunology. 36:879-881.
PubMed Reference
UI: 79172020

Yamamoto A, Wada O, Suzuki H. (1987) Purification and properties of biologically active chromium complex from bovine colostrum. American Institute of Nutrition. 118(1):39-45.
PubMed Reference
UI: 88089963

Zhang T, Iguchi K, Mochizzuki T, Hoshino M, Yanaihara C, Yanaihara N. (1990) Gonadotropin-releasing hormone-associated peptide immunoreactivity in bovine colostrum. Society for Experimental Biology and Medicine. 194(3):270-3.
PubMed Reference
UI: 90287898

Growth Factors

Antonio J. (1998) Can bovine colostrum enhance levels of IGF-1? Muscle and Fitness.

Ballard F, Wallace J, Francis G, Read L, Tomas F. (1996) Des (1-3) IGF-I: a truncated form of insulin-like growth factor-I. International Journal of Cellular Biology. 28:1085-1087.
PubMed Reference
UI: 97083788

Bricker D. (1991) Colostrum: Implications for accelerated recovery in damaged muscle and cartilage, prevention of some pathogenic disease. The American Chiropractor.

Burrin D, Davis T, Ebner S, Schoknecht P, Fiorotto M, Reeds P. (1997) Colostrum enhances the nutritional stimulation of vital organ protein synthesis in neonatal pigs. American Society for Nutritional Sciences. 127(7):1284-9.
PubMed Reference
UI: 97347442

Bhora F, Dunkin, B, Batzri S, et al. (1995) Effect of growth factors on cell proliferation and epithelialization in human skin. Journal of Surgery Res. 59:236-244.
PubMed Reference
UI: 95364356

 

Burrin DG, Shulman RJ, Reeds PJ, Davis TA, Gravitt KR. (1992) Porcine colostrum and milk stimulate visceral organ and skeletal muscle protein synthesis in neonatal piglets. Journal of Nutrition. 122:1205-1213.
PubMed Reference
UI: 92269024

Cass TL. Insuin-like growth factor-1 (IGF-1, Somatomedin C) blood levels are not associated with prostate specific antigen (PSA) levels or prostate cancer: A study of 749 patients. Medical College of Wisconsin, Milwaukee, WI www.worldhealth.net/news/prost-igf1/:1999.

Demarco C. (1998) Anti-aging breakthrough: Homeopathic growth factors. Let's Live.

Francis G, Upton F, Ballard J, McNeil K, Wallace J. (1988) Insulin-like growth factors 1 and 2 in bovine colostrum. Journal of Biochemistry. 251:95-103.
PubMed Reference
UI: 88268820

Fryburg D. (1995) Insulin and insulin-like growth factor 1 enhance human skeletal muschle protein anabolism during Hyperaminoacidemia by different mechanisms. Journal of Clinical Investigations 96:1722-1729.
PubMed Reference
UI: 96013632

Francis G, Read L, Ballard J, et al. (1986) Purification and partial sequence analysis of insulin-like growth factor-1 from bovine colostrum. Journal of Biochemistry 233:207-213.
PubMed Reference
UI: 86158708

Ginjala V, Pakkanen R. (1998) Determination of transforming growth factor-B1 (TGF-B1) and insulin-like growth factor 1 (IGF-1) in bovine colostrum samples. Journal of Immunoassay 19:195-207.
PubMed Reference
UI: 98347053

 

Hadsell KL, Baumrucker CR, Kensinger RS. (1993) Effects of elevated blood insulin-like growth factor-I (IGF-I) concentration upon IGF-I in bovine mammary secretions during the colostrum phase. Journal of Endocrinology. 137:223-230.
PubMed Reference
UI: 93316008

Juskevich J. (1990) Bovine Growth Hormone: Human Food Safety Evaluation. Science. 249:875-883.

Kirkpatrick CH.(1993) Structural nature and functions of transfer factors. Annals New York Academy of Sciences. 685:362-8.
PubMed Reference
UI: 93370874

Marcotty C, Frankenne F, Van Beeumen J, Maghuin-Rogister G, Hennen G. (1991) Insulin-like growth I (IGF-I) from cow colostrum: Purification and characterization. Growth Regulation. 1(2):56-61.
PubMed Reference
UI: 93091807

Marquardt H, Lioubin MN, Ikeda T. (1987) Complete amino acid sequence of human transforming growth factor type beta 2. Journal of Biological Chemistry. 262:12127-12131.
PubMed Reference
UI: 87308213

Miers W, Barrett E. (1998) The role of insulin and other hormones in the regulation of amino acid and protein metabolism in humans. Journal of Basic and Clinical Physiology and Pharmacology. 9(2-4):235-53.
PubMed Reference
UI: 99229307

 

Noda K, Umeda M, Ono T. (1984) Transforming growth factor activity in human colostrum. Gann. 75:109-112.
PubMed Reference
UI: 84237261

Nowak J, Olszewski J, Kozal E. (1994) Insulin and sugar concentration changes in mammary secretion in sheep during the periparturient period. Reprod. Nutritional Development. 34:3-8.
PubMed Reference
UI: 94176019

Nowak J. (1990) Insulin and glucose concentration changes in newborn piglets after suckling the colostrum from insulin administered sows. Acta Physiol. 41(7):155-62.
PubMed Reference
UI: 92351771

Nord J, Ma P, DiJohn D, Tzipori S, Tacket CO. (1990) Treatment with bovine hyperimmune colostrum cryptosporidial diarrhea in AIDS patients. AIDS. 4:581-584.
PubMed Reference
UI: 90351575

Oda S, Satoh H, Sugawara T, et al. (1989) Insulin-like growth factor-I, GH, insulin and glucagon concentrations in bovine colostrum and in plasma of dairy cows and neonatal calves around parturition. Comp. Biochemical Physiology. 94A:805-808.
PubMed Reference
UI: 90151056

Pakkanen R, Aalto J. (1997) Review paper: Growth factors and antimicrobial factors of bovine colostrum. International Dairy Journal. 7:285-297.

Pakkanen R. (1998) Determination of transforming growth factor-B2 (TGF-B2) in bovine colostrum samples. Journal of Immunoassay. 19:23-37.

PubMed Reference

Rosenthal S, Brown E, Brunetti A, Goldfine I. (1991) Fibroblast growth factor inhibits insulin-like growth factor-II (IGF-II) gene expression and increases IGF-I receptor abundance in BC3H-1 muscle cells. Molecular Endocinology. 5:678-684.
PubMed Reference
UI: 91304432

Russell J, Feldman E. (1999) Insulin-like growth factor-I prevents apoptosis in sympathetic neurons exposed to high glucose. Horm Metab Res. 31:90-96.
PubMed Reference
UI: 99243374

Sara VR, Hall K. (1990) Insulin-like growth factors and their binding proteins. Physiological Reviews. 70:591-606.

Shimizu M, Webster C, Morgan DO, Blau HM, Roth RA. (1986) Insulin and insulin-like growth factor receptors and responses in cultured human muscle cells. American Journal of Physiology. 251:E611-5.

Shing Y, Klagsbrun M. (1987)Purification and characterization of a bovine colostrum-derived growth factor. Molecular Endocrinology. 1:335-338.
PubMed Reference
UI: 90331924

Skottner A, Arrhenius-Nyberg V, Kanje M, Fryklund L. (1990) Anabolic and tissue repair functions of recombinant insulin-like growth factor I. Acta Pediatric Scand. 367:63-66.
PubMed Reference
UI: 91022017

 

Sporn M, Roberts A, Shull J, Smith J, Ward J. (1983) Polypeptide transforming growth factors isolated from bovine sources and used for wound healing in vivo. Science. 219(4590): 1329-31.
PubMed Reference
UI: 83146345

Tokuyama H, Tokuyama Y, Migita S. (1990) Isolation of two new proteins from bovine colostrum which stimulates epidermal growth factor-dependent colony formation of NRK-49F cells. Growth Factors. 3(2):105-14.
PubMed Reference
UI: 91000711

Tokuyama Y. (1993) Purification and identification of TGF-B2-related growth factor from bovine colostrum. Journal of Dairy Research. 60:99-109.
PubMed Reference
UI: 93171372

Tollefsen S, Lajara R, McCusker R, Clemmons D, Rotwein P. (1989) Insulin-like growth factors (IGF) in muscle development. Journal of Biological Chemistry. 264(23):13810-7.
PubMed Reference
UI: 89340472

Tomas F, Knowles S, Owens P, et al. (1991 ) Increased weight gain, nitrogen retention and muscle protein synthesis following treatment of diabetic rats with insulin-like growth factor (IGF)-I and des(1-3)IGF-I. Biochem J. 276 ( Pt 2):547-54.
PubMed Reference
UI: 91264814

Tokuyama, H. and Tokuyama, Y. (1989) Bovine colostric transforming growth factor-B like peptide that induces growth inhibition and changes in morphology of human osteogenic sarcoma cells (MG-63). Cell Biology International Reports 13:251-258.
PubMed Reference
UI: 89208792

 

Ullman M, Ullman A, Sommerland H, Skottner A, Oldfors A. (1990) Effects of growth hormone on muscle regeneration and IGF-I concentration in old rats. Acta Physiological Scand 140:521-525.

Shomali M, Wolfsthal S. (1997) The use of anti-aging hormones. Maryland Medical Journal 46:181-186.
PubMed Reference
UI: 91188893

Watson DL, Francis GL, Ballard FJ. (1992) Factors in ruminant colostrum that influence cell growth and murine IgE antibody responses. Journal of Dairy Research 59:369-380.
PubMed Reference
UI: 93017233

Immune Factors

Bocci V, Von Bremen K, Corradeschi F, Luzzi E, Paulesu L. (1991) What is the role of cytokines in human colostrum? Journal of Biological Regulators and Homeostatic Agents. 3:121-124.
PubMed Reference
UI: 92206191

Boesman-Finkelstein M. and Finkelstein R. (1989) Passive oral immunisation of children. Lancet. 2(8675):1336.
PubMed Reference
UI: 90081062

Bogstedt AK, Johansen K, Hatta H, et al. (1996) Passive immunity against diarrhoea. Acta Paediatr. 85:125-128.
PubMed Reference
UI: 96233729

 

Casswall T, Sarker S, Albert M, et al. (1998) Treatment of Helicobacter pylori infection in infants in rural Bangladesh with oral immunoglobulins from hyperimmune bovine colostrum. Ailment Pharmacol Therapies 12:563-568.
PubMed Reference
UI: 98341957

Davidson G, Whyte P, Daniels E, et al. (1989) Passive immunisation of children with bovine colostrum containing antibodies to human rotavirus. Lancet. 2(8665):709-12.
PubMed Reference
UI: 89383719

Dichtelmuller W, Lissner R. (1990) Antibodies from colostrum in oral immunotherapy. Journal of Clinical Biochemistry 28:19-23.
PubMed Reference
UI: 90188232

Ebina T, Umezu K, Ohyama S, et al. (1983) Prevention of rotavirus infection by cow colostrum containing antibody against human rotavirus. Lancet. 2(8357):1029-30.
PubMed Reference

Feldmann M, Brennan F, Maini R. Role of cytokines in rheumatoid arthritis. Annual Review of Immunology 14:397-440, 1996.
PubMed Reference

Hanson LA, Ahlstedt S, Andersson B, et al. (1983) Mucosal Immunity. Annals New York Academy of Sciences 83:1-20.

Boesman-Finkelsein M, Walton NE, Finkelstein RA. (1989) Bovine lactogenic immunity against cholera toxin-related enterotoxins and Vibrio cholerae outer membranes. Infection and Immunity 57:1227-1234.
PubMed Reference
UI: 89173323

Hilpert H, Brussow H, Mietens C, Sidoti J, Lerner L, Werchau H. (1987) Use of bovine milk concentrate containing antibody to rotavirus to treat rotavirus gastroenteritis in infants. Journal of Infectious Diseases 156:158-166.
PubMed Reference
UI: 87252383

 

Hirmo S, et al. (1998) Characterization of Helicobacter pylori interactions with sialylglycoconjugates using a resonant mirror biosensor. Analytical Biochemistry 257:63-6.
PubMed Reference
UI: 98173929

Hoffman M. (1992) Transferred immune cells may help fight viral infection. Immunology. 257(5067):166.
PubMed Reference
UI: 92335854

Honorio-Franca A, Carvalho M, Isaac L, Trabulsi L, Carneiro-Sampaio M. (1997) Colostral mononuclear phagocytes are able to kill enteropathogenic Escherichia coli opsonized with colostral IgA. Scandavian Journal of Immunology. 46:59-66.
PubMed Reference
UI: 97388992

Huppertz H, Rutkowski S, Busch D, Eisebit R, Lissner R, Karch H. (1999) Bovine colostrum ameliorates diarrhea in infection with diarrheagenic Escherichia coli, shiga toxin producing E. coli, and E-coli expressing intimin and hemolysin. Journal of Pediatric Gastroenterology and Nutrition. 29:452-456.
PubMed Reference
UI: 99440959

Janusz M, Lisowski J. (1993) Proline-rich polypeptide (PRP)-an immunomodulatory peptide from ovine colostrum. Archivum Immunologiae et Therapiae Experimentalis. 41:275-279.

Jochims K, Kaup F, Drommer W, Pickel M. (1994) An immunoelectron microscopic investigation of colostral IgG absorption across the intestine of newborn calves. Research in Veterinary Science. 57:75-80.
PubMed Reference
UI: 95063344

 

Kelly CP, et al. (1996) Anti-Clostridium difficile bovine immunoglobulin concentrate inhibits cytotoxicity and enterotixicity of C. difficile toxins. Antimicrobial Agents and Chemotherapy 40:373-379.
PubMed Reference
UI: 96431801

Kelly G. (1999) Larch arabinogalactan: Clinical relevance of a novel immune-enhancing polysaccharide. Alternative Medicine Review. 4(2):96-103.
PubMed Reference
UI: 99250542

Khazenson L, Gennad'eva T, Roshchin V, Krasheniuk A, Semenova N. (1980) Activity of bovine colostral IgG in the human digestive tract. ZH Mikrobiol Epidemiol Immunobiol 9:101-106.
PubMed Reference
UI: 81081866

Kohl S, Malloy, M, Pickering L, Morriss F, Adcock E, Walters D. (1978) Human colostral cytotoxicity: I. Antibody-dependent cellular cytotoxicity against herpes simplex viral-infected cells mediated by colostral cells. Journal of Clinical Laboratory Immunology. 1:221-224.
PubMed Reference
UI: 80051884

Korhonen H, Suvaoja EL, Ahola-Luttilia H, et al. (1995) Bactericidal effect of bovine normal and immune serum, colostrum and milk against Helicobactor pylori. Journal of Applied Bacteriology 78:655-662.
PubMed Reference
UI: 95340389

Lawton JW, Shortridge KF, Wong RL, Ng MH. (1979) Interferon synthesis by human colostral leucocytes. Archives of Disease in Childhood 54:127-130.
PubMed Reference
UI: 79164511

 

LeFranc-Millot C, Vercaigne-Marko D, Wal J.-M, et al. (1996) Comparison of the IgE titers to bovine colostral G immunoglobulins and the F(ab')2 fragments in sera of patients allergic to milk. Int Arch Allergy Immunol. 110:156-162.
PubMed Reference
UI: 96242068

Leszek J, Inglot AD, Janusz M, Lisowski J, Krukowska K, Georgiades JA. (1999) Colostrinin: a Proline-Rich Polypeptide (PRP) Complex Isolated from Ovine Colostrum for Treatment of Alzheimer's Disease. A Double - Blind Placebo-Controlled Study. Archivum Immunologiae et Therapiae Experimentalis. 47(6):377-85.
PubMed Reference
UI: 20073974

Lissner R, Thurmann P, Merz G, Karch, H. (1998) H. Antibody reactivity and fecal recovery of bovine immunoglobulins following oral administration of a colostrum concentrate from cows to healthy volunteers. International Journal of Clinical Pharmacology and Therapeutics 36:239-245.
PubMed Reference
UI: 98291938

Loimaranta V, Carlen A, Olsson J, Tenovuo J, Syvaoja E.-L, Korhonen H. (1998) Concentrated bovine colostral whey proteins from Streptococcus mutans/Strep. sobrinus immunized cows inhibit the adherence of Strep. mutans and promote the aggregation of mutans streptococci. Journal of Dairy Research 65:599-607.
PubMed Reference
UI: 99056594

McClead RE, Butler T, Rabbani GH. (1988) Orally Administered Bovine Colostral Anti-Cholera Toxin Antibodies: Results of Two Clinical Trials. The American Journal of Medicine 85:811-816.
PubMed Reference
UI: 89060326

 

Michalek SM, McGhee JR. (1977) Effective immunity to dental caries: passive transfer to rats to antibodies to Streptococcus mutans elicits protection. Infection and Immunity 17:644-650.
PubMed Reference
UI: 78004961

Michalek SM, McGhee JR, Babb JL. (1978) Effective immunity to dental caries: dose-dependent studies of secretory immunity by oral administration of Streptococcus mutans to rats. Infection and Immunity. 19:217-224.
PubMed Reference
UI: 78108593

Mitra AK, Mahalanabis D, Ashraf H, Unicomb L, Eeckels R, Tzipori S. (1995) Hyperimmune cow colostrum reduces diarrhoea due to rotavirus: a double-blind, controlled clinical trial. Acta Paediatr. 84:996-1001.
PubMed Reference
UI: 96112936

Moro I, Abo T, Crago SS, Komiyama K, Mestecky J. (1985) Natural Killer Cells in Human Colostrum. Cellular Immunology. 93:467-474.
PubMed Reference
UI: 85228319

Naber P, et al. (1996) Inhibition of adhesion of Clostridium difficile to caco-2 cells. Immunology and Medical Microbiology. 14:205-209.
PubMed Reference
UI: 97009214

Ouwehand A, Salminen S, Skurnik M, Conway P. (1997) Inhibition of pathogen adhesion by B-lactoglobulin. International Dairy Journal. 7:685-692.

Ogra P, Losonsky G, Fishaut M. (1983) Colostrum-derived immunity and maternal-neonatal interaction. New York Academy of Science 409:82-95.
PubMed Reference
UI: 83254462

Ogra SS, Ogra PL. (1978) Immunologic aspects of human colostrum and milk. The Journal of Pediatrics. 92:546-549.
PubMed Reference
UI: 78132263

Palmer EL, Gary Jr. GW, Black R, Martin ML. (1980) Antiviral activity of colostrum and serum immunoglobulins a and g. Journal of Medical Virology. 5:123-129.
PubMed Reference
UI: 80184004

Parodi PW. (1996) Milk fat components: possible chemopreventive agents for cancer and other diseases. The Australian Journal of Dairy Technology. 51:24-32.

Petschow B, Talbott R. (1994) Reduction in virus-neutralizing activity of a bovine colostrum immunoglobulin concentrate by gastic acid and digestive enzymes. Journal of Pediatric Gastroenterology and Nutrition . 19:228-235.
PubMed Reference
UI: 95114795

Plettenberg A, Stoehr.A, Stellbrink.J, Albrecht.H, Meigel W. (1993) A preparation from bovine colostrum in the treatment of HIV-posotive patients with chronic diarrhea. Clinical Investigator 71:42-45.
PubMed Reference
UI: 93200737

Pincus C, Nussenweig V. (1971) Regulation of the Immune Response: Suppressive and enhancing effects of passively administered antibody. Journal of Experimental Medicine. 133:987-1003.
PubMed Reference
UI: 71165668

Pironi L, Miglioli M, Ruggeri E, et al. (1990 ) Relationship between intestinal permeability to EDTA and Inflammatory activity in asymptomatic patients with Crohn's disease. Digestive Diseases and Sciences. 35(5):582-8.
PubMed Reference
UI: 90235714

 

Quigley JD, Martin KR, Dowlen HH, Wallis LB, Lamar K. (1994) Immunoglobulin concentration, specific gravity, and nitrogen fractions of colostrum from Jersey cattle. Journal of Dairy Science. 77:264-269.
PubMed Reference
UI: 94165259

Rautiainen E. (1998) The prevalence of Mycoplasma hyopneumoniae in pig herds in western Finland based on the demonstration of antibodies in colostrum by ELISA. Acta Vet Scand. 39:325-330.
PubMed Reference
UI: 99003763

Ritchie D, Becker E. (1994) Update on the management of intestinal cryptosporidiosis in AIDS. The Annals of Pharmacotherapy. 28:767-778.
PubMed Reference
UI: 95003254

Robert Service. (1994) Triggering the First Line of Defense. Research News. 265.
PubMed Reference
UI: 94360236

Rump JA, Arndt R, Arnold A, et al. (1992)Treatment of diarrhoea in human immunodeficiency virus-infected patients with immunoglobulins from bovine colostrum. Clinical Investigator. 70:588-594.
PubMed Reference
UI: 93005401

Saif L, Smith K. (1985) Enteric viral infections of calves and passive immunity. Journal of Dairy Science. 68:206-228.
PubMed Reference
UI: 85158472

Sandholm M, Honkanen-Buzalski T. (1979) Colostral trypsin-inhibitor capacity in different animal species. Acta Vett.Scand. 20:469-476.
PubMed Reference
UI: 80195445

 

Sarker S, Casswall T, Mahalanabis M, et al. (1998) Successful treatment of rotavirus diarrhea in children with immunoglobulin from immunized bovine colostrum. Pediatric Journal of Infectious Disease. 17:1149-54.
PubMed Reference
UI: 99093192

Savilahti E, Tainio VM, Salmenpera L, Arjomaa P, Kallio M, Perheentupa J, Siimes MA. (1991) Low colostral IgA associated with cow's milk allergy. Acta Pediatr Scan. 80:1207-1213.
PubMed Reference
UI: 92151656

Selo I, Clement G, Bernard H, et al. (1999) Allergy to bovine B-lactoglobulin: specificity of human IgE to tryptic peptides. Clinical and Experimental Allergy 29:1055-1063.
PubMed Reference
UI: 99388301

Shearman D. (1972) The demonstration and function of antibodies in the gastrointestinal tract. Gut. 13(6):483-99.
PubMed Reference
UI: 72254526

Shortridge K, Lawton J, Choi E. (1990) Protective potential of colostrum and early milk against prospective influenza viruses. Journal of Tropical Pediatrics. 36(2):94-5.
PubMed Reference
UI: 90286002

Siber G. (1992) Immune globulin to prevent nosocomial infection. New England Journal of Medicine. 327(4):269-71.
PubMed Reference
UI: 92310493

Stephen W, Dichtelmuller H, Lissner R. (1990) Antibodies from colostrum in oral immunotherapy. Journal of Chemical Clinical Biochemistry 28:19-23.
PubMed Reference
UI: 90188232

 

Staroscik K, Janusz M, Zimecki M, Wieczorek Z, Lisowski J. (1983) Immunologically active nonapeptide fragment of a proline-rich polypeptide from ovine colostrum: amino acid sequence and immunoregulatory properties. Molecular Immunology. 12:1277-1282.
PubMed Reference
UI: 84093156

Swarbrick ET. (1992) The handling of ingested antigens. Am J Trop Med Hyg. 47(3):276-83.
PubMed Reference
UI: 92397977

Tacket CO, Binion SB, Bostwick E, Losonsky G, Roy MJ, Edelman R. Efficacy of bovine milk immunoglobulin concentrate in preventing illness after Shigella flexneri challenge. Am. J. Trop. Med. Hyg. 47:276-283, 1992.

Takahashi, T. and et al. (1998) Effects of Orally Ingested Bifidobacterium longum on the Mucosal IgA response of Mice to Dietary Antigens. Biosci Biotechnol Biochem. 62(1):10-5.
PubMed Reference
UI: 98162133

Tejada-Simon M, Lee J, Ustunol Z, Pestka J.( 1999) Ingestion of yogurt containing lactobacillus acidophilus and bifidobacterium to potentiate immunoglobulin A responses to cholera toxin in mice. Journal of Dairy Science 82:649-660.
PubMed Reference
UI: 99228922

Tyler J, Stevens B, Hostetler D, Holle J, Denbigh J. (1999) Colostral immunoglobulin concentrations in holstein and guernsey cows. American Journal of Veterinary Research. 60(9):1136-9.
PubMed Reference
UI: 99418617

Tzipori S, Roberton D, Chapman C. (1986) Remission of diarrhoea due to cryptosporidiosis in an immunodeficient child treated with hyperimmune bovine colostrum. British Medical Journal. 293(6557):1276-7.
PubMed Reference
UI: 87050670

 

Ulcova-Gallova Z, Fialova P, Krauz V. (1994) Immunologic factors in human colostrum and milk. Casopis Lekaru Ceskych 133:275-276.
PubMed Reference
UI: 94251804

Ungar BLP, Ward DJ, Fayer R, Quinn CA. (1990)Cessation of Cryptosporidium-associated diarrhea in an acquired immunodeficiency syndrome patient after treatment with hyperimmune bovine colostrum. Gastroenterology . 98:486-489.
PubMed Reference
UI: 90108566

Ushijima H, Dairaku M, Honnma H, Mukoyama A, Kitamura T. (1990) Immunoglobulin components and anti-viral activities in bovine colostrum. 64:274-279.
PubMed Reference
UI: 90293546

Veselsky L, Cechova D, Jonakova V. (1978) Secretion and Immunochemical Properties of the Trypsin Inhibitor from Bovine Colostrum. Hoppe-Seyl